Virtual Conference

Track: Cancer Stem Cells

Cancer Stem Cells


Cancer stem cells are a distinct population of cells within tumors that possess characteristics similar to normal stem cells. These cells have the ability to self-renew and differentiate into different cell types within the tumor. They are believed to play a crucial role in tumor initiation, growth, metastasis, and resistance to treatment. Cancer stem cells have unique properties that contribute to their significance in cancer biology. They have the capacity for self-renewal, allowing them to regenerate and sustain the tumor over time. Additionally, they can differentiate into various cell types within the tumor, contributing to its heterogeneity. These cells are often resistant to conventional cancer treatments, such as chemotherapy and radiation therapy, which primarily target rapidly dividing cells. Their resistance is thought to be due to their slow-cycling nature, enhanced DNA repair mechanisms, and increased expression of drug efflux pumps. The presence of cancer stem cells in tumors has important clinical implications. They are associated with tumor recurrence and metastasis, as even a small population of these cells can repopulate the tumor after treatment. Targeting cancer stem cells is therefore an active area of research, with the aim of developing therapies that can eliminate these cells and prevent disease relapse.
·        Stem cell mutation
·        De-differentiation
·        Metastasis
·        CSC-specific agents
·        miRNA expression