Zakir Hossain Habib

Institute of Epidemiology Disease Control And Research IEDCR, Bangladesh

Title: Burden of hospital acquired blood stream infection in comorbid patients in tertiary care hospitals of Bangladesh

Abstract

Background: Bloodstream infections (BSIs) are the most severe infections that cause high mortality and longer hospital stay of the patients specially if it is caused by Hospital Acquired Infections (HAI). Diseases associated with an increased risk of BSI include comorbid conditions of the patients like malignancies, diabetes mellitus, Chronic Kidney Disease (CKD) requiring dialysis, chronic hepatic failure; immune deficiency syndromes and burns. In this study we aimed to investigate the role of comorbidity in causing hospital acquired BSIs and the pathogens causing it.

Method: In this retrospective study, the data was analyzed from the National Antimicrobial Resistance (AMR) surveillance system of Bangladesh. We analyzed all the available data from 2017 to 2023 from eleven tertiary care hospitals situated in different geographical locations of Bangladesh. The blood samples were collected from the patients who were presented with bloodstream infections according to standard case definition and HAI was identified if pathogenic organisms were isolated after 48 hours of hospitalization. The bacterial isolates were cultured as per standard protocol in the sentinel site microbiology laboratories and the antimicrobial susceptibility testing was performed by Kirby–Bauer disc diffusion method to determine the susceptibility. All the statistical analysis was performed using Stata version 14 (College Station, TX, USA).

Results: Among 5,225 blood samples tested, 819 (15.67%) yielded growth. We have examined the associations between comorbidities such as diabetes, CKD, chronic liver disease (CLD), and cancer among 294 patients with HAI. CKD showed a significant association across all admitted patients ( ICU and non-ICU indoor patients) , whereas CKD and cancer were associated with non-ICU indoor patients only, and diabetes with ICU patients exclusively.

Conclusion: BSI due to HAI is common in hospitals and comorbidity of the patients increases the vulnerability of the patients which is found in the study. Further extensive research is required to elucidate this association more comprehensively.

Biography

TBA

4th International Conference on Oncology and Research Treatment

Zakir Hossain Habib

Title: Burden of hospital acquired blood stream infection in comorbid patients in tertiary care hospitals of Bangladesh

Abstract

Biography

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