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Suzy Ramos Rocha

University of São Paulo, Brazil

Title: Functional capacity of women with breast neoplasm undergoing palliative chemotherapy

Abstract

Purpose: 
To evaluate the functional capacity of women with breast neoplasm undergoing palliative chemotherapy. Background: Breast neoplasm have the highest incidence and mortality rate among women worldwide. In Brazil, 38% of diagnosed women have worse prognosis and low survival, which directs therapeutic efforts to extended or exclusive palliative care. Methods: Cross-sectional study, ethically approveded, with a no probabilistic sample of 100 medical records of breast cancer women 18 or older submitted to outpatient palliative chemotherapy during 2018 in the National Cancer Institute, Rio de Janeiro. From june to september 2019, the authors developed and applied 27 questions to evaluate socioeconomic characteristics, lifestyle and previous and/or current diseases/oncological treatment, the performance status (PS/ECOG - score value 0,1,2,4,5). Univariate analysis was carried out through chi-squared Pearson test between the PS scale and the other variables (p ? 0.005). Outcomes: 66% of the sample were < 50 years, 53% with primary education, 87% income of 1 to 2 wages, 62% unemployed, 43% single/divorced/widow, 45% had some comorbidity. Regarding clinical data, 95% had invasive ductal carcinoma, with positive hormone receptor (64%) and histological grade 1 and 2 (57%).  75% were oncological treatment prior to palliative chemotherapy, 50% have bone and visceral metastasis,  68% asthenia, 55% fatigue, 53% pain, 53% nausea and vomits.  Chemotherapy schemes were associated with inappetence (p=0.00) and weight loss (p=0.001) symptoms. From all complications, 31% were neuropathy, 21% medullary compression syndrome, 9% neutropenia and 28% death. Performance status 0 (49%), 1 (39%), and 2 (12%) were prevalent (mild and moderate activity restriction). Discussion and Implications:. Despite the majority women were PS 0 and 1, most of them have social vulnerability, manageable symptoms and other moderate or severe complications, even occurring early death. Thus, the monitoring of functional capacity is essential for better flow assistance, improve social support and women's quality survival.

Biography

Nurse graduated from the Federal University of Ceará (2010 to 2014), with integration to the Maternal and Mammary Health Research and Extension Project (2010-2017), with an emphasis on breast cancer care. Specialist in Emergency at the State University of Ceará (2017). Master in Nursing in Health Promotion from the Federal University of Ceará (2017). Specialist in Stomatherapy from the State University of Rio de Janeiro (2019). Specialist in the residency modality in Oncology by the National Cancer Institute (2020). She is currently a student of the Doctoral Course of the Postgraduate Program in Nursing in Adult Health-PROESA (2020-current).