Mykhailo Iegorov
National Cancer Institute, UkraineTitle: A rare case of disseminated peritoneal leiomyomatosis in a patient with a history of recurrent widespread endometriosis
Abstract
Leiomyomatosis peritonealis disseminata (LPD) is a benign disease characterized by the presence of multiple nodular formations spread over the peritoneum, similar to metastases of a malignant tumor, but having the histological structure of leiomyoma and characterized by prognostically favorable course. The presented clinical case describes the disease of a 47-year-old patient who previously underwent surgical treatment of uterine leiomyoma in combination with endometriosis, followed by repeated surgical operations for widespread recurrent endometriosis. 11 years after the primary operation, the patient was referred to the oncogynecologist with suspected carcinomatous lesions of the peritoneum and pleura. Ultrasound data and cytology of ascitic and pleural fluid refuted the malignant process, the patient underwent lower-mid laparotomy, multiple biopsy of peritoneal heterotopias, resection of the omentum. According to the results of further morphological and immunohistochemical studies, the resulting phenotype of the tumor corresponds to LPD with foci similar to a smooth muscle tumor with an uncertain malignancy potential.
Biography
Mykhailo Iegorov has completed his PHD at the age of 37 years from P.L. Shupik Medical Academy of Postgraduate Education of Ministry of Health, Ukraine. He is the Senior Researcher of the Scientific and Clinical Department of Female Reproductive System Neoplasms in National Cancer Institute, Kyiv, Ukraine. Area of scientific interests of him is the treatment of disseminated neoplasms of the female reproductive system. He has over 10 publications on this topic 2 of which are included to Scopus database. He is an external reviewer for the journal Experimental Oncology.
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