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Djiwa Toukilnan

University of Lomé, Togo

Title: Renal Leiomyosarcoma, a Rare Presentation

Abstract

Renal sarcomas are very rare malignant tumours with a very poor prognosis. Renal leiomyosarcoma, a malignant tumour of smooth muscle origin, is the most common histological type. The article reports a case of leiomyosarcoma of renal location, with a review of the literature. A 38-year-old female patient, with no previous pathological history, consulted the nephrology department of the Teaching Hospital of Lomé for abdominal pain that had been present for 4 years. Histology showed a tumour proliferation of fasciculated architecture, made of spindle cells arranged in long bundles, with cytonuclear atypia and cytoarchitectural abnormalities. Immunohistochemical examination showed positive staining for smooth muscle actin, h-caldesmone, desmin and CD34 and negative for pancytokeratin (AE1/AE3), myogenin and PS100. Renal leiomyosarcoma is an exceptional malignancy. It remains the most common renal sarcoma, the differential diagnosis of which is based on immunohistochemical findings.

Biography

Djiwa Toukilnan has completed his PHD at the age of 25 years from University of Lomé, Togo. He is an Assistant professor at the Faculty of Medicine of the University of Lomé, specialist in cancerous and inflammatory pathologies. He has over 50 publications that have been cited over 100 times. He has been serving as an editorial board member of several journals.