Objective: To synthesize the best available evidence on the effectiveness of nursing interventions in radiotherapy patient care and to summarize the evidence on the experience and acceptability of interventions reported by health professionals involved in the prevention and treatment of side effects. Method: A mixed-method systematic review. Quantitative and qualitative studies are presented. Results: Twelve studies published between 2013 and 2017 were included. Most interventions found focused on skin care, oral care, nausea and vomiting, and nursing consultation. In accordance with the high level of evidence and recommendation grade of the studies, the use of Calendula officinalis and thyme honey were considered effective for preventing and treating radiodermatitis and mucositis, respectively. Conclusion: The quality of evidence of nursing interventions is weak. Although there are studies with a strong design and a high level of evidence, the publication of nursing interventions is not enough and does not present a high quality to support practice to plan effective patient-centered care. Descriptors: Neoplasms; Radiotherapy, Oncology Nursing; Patient-Centered Care; Review

Aline Moraes de Abreu completed her Master's at the age of 32 at the Federal University of Health Sciences in Porto Alegre, Brazil. He is the coordinator of Radiotherapy at Hospital Mãe de Deus, Brazil. PhD student at the PPG Biosciences at UFCSPA