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Aleksei Tsybulskii
Russian Scientific Center of Roentgenoradiology, Russian FederationPresentation Title:
Effect of polyacrylamide-based gel spacers on dose distribution and rectal toxicity during high-dose-rate brachytherapy for prostate cancer
Abstract
Recently, modern concepts in radiobiology and radiation therapy in the treatment of prostate cancer imply a transition to hypofractionated treatment regimens. High dose rate brachytherapy is one of the effective methods of radiation therapy that allows you to work in ultrahypofractionation modes, often using 2-3 fractions over the entire course of treatment. The dose to the anterior wall of the rectum during high dose rate brachytherapy in the treatment of prostate cancer can be significantly reduced through the use of hydrogel spacers based on polyacrylamide (PAGE). In order to reduce the radiation load on the anterior wall of the rectum during brachytherapy, we implanted a volume-forming biosoluble synthetic gel based on polyacrylamide at a depth of 5 ml between the prostate gland and the anterior wall of the rectum. PAGE spacers are safe to insert. Gel implantation is simple, quick and has a low complication rate. Retracting the anterior wall of the rectum away from the prostate gland allows for optimization of dose distribution during high dose rate brachytherapy.
Biography
Aleksei Tsybulskii has completed his PHD at the age of 41 years from Russian Scientific Center of Roentgenoradiology. He is the Leading Researcher of Russian Scientific Center of Roentgenoradiology. Head of division and brachytherapy surgical team, the Department of Urologic Oncology and Andrology, Urology unit of Russian Scientific Center for Roentgen Radiology. More than 450 surgeries (high dose-rate and low dose-rate brachytherapy) are performed each year. He has over 80 publications that have been cited over 700 times, and his publication h-index is 8.
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