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Valeriia Chetverikova-Ovchynnyk

Odessa National Medical University, Ukraine

Title: TBA

Abstract

The perioperative practice of the cytoreductive surgery (CRS) management varies among different oncology centers, due to the lack of a unified approach, the small number of patients, and different volume of surgery performed. The enhanced recovery after surgery (ERAS) aims to standardize and optimize perioperative care for patients with peritoneal carcinomatosis (PC). The aim of the study was to investigate the validity of the Enhanced recovery after surgery (ERAS) protocol for patients with peritoneal carcinomatosis of different primary origins undergoing CRS with or without hyperthermic intraperitoneal chemotherapy (HIPEC) based on the clinical outcomes (the length of hospital stay (LOS), return of bowel function, postoperative complications) and quality of life (QLQ) analysis. Materials and methods. The ERAS protocol included a perioperative approach to the treatment of patients with PC. The study included a total of 304 patients, who underwent cytoreductive surgery with or without HIPEC. Patients were divided into 2 groups: Group I (nonERAS) — 178 patients and Group II (ERAS) — 126 patients. Results. There was a significant difference between LOS in both groups (11.8 ± 3.7 in I Group (nonERAS) and 6.4 ± 2.1 in II Group (ERAS)) (p <0,01). The use of ERAS protocol facilitates the earlier return of bowel function (peristalsis and stool) in the postoperative period (p <0,01). There was no significant difference in the incidence of postoperative complications between ERAS and nonERAS groups. Improved quality of life (estimated by the EORTC QLQ C30 questionnaire) was achieved due to the ERAS protocol. Conclusions. The obtained data prove the clinical safety and feasibility of the implemented ERAS protocol for patients undergoing CRS. The shorter LOS and better QLQ due to ERAS allow patients to start rehabilitation and subsequent stages of special treatment earlier and to reduce the financial costs.

Biography

Valeriia Chetverikova-Ovchynnyk works as a postgraduate in Odessa National Medical University, Ukraine. She has completed her fellowship in the Center of Reconstructive and Restorative Medicine (University Clinic) of Odessa National Medical University as a surgeon. Her clinical and research interests include gastrointestinal tumors, surgery management of peritoneal carcinomatosis of different primary origin. She works as a member of a multidisciplinary oncology team in the Center of Reconstructive and Restorative Medicine (University Clinic).