Vulvar cancer treatment depends on the stage, when possible, surgery is preferable. Surgery resects the tumor plus a margin of 1.5 cm. Advanced cancers require large resections, which often need grafts, rotating flaps, radio, and/or chemotherapy. They can produce serious adverse effects. We incorporate cryosurgery as an option, where these effects are minimized.  Technique: Previous evaluation usual. First, we remove the tumor in the block but without a safety margin.  Hemostasis and 2 freeze-thaw cycles with nitrogen liquid spray. Freezing includes lodge and safety margin, should be done rapidly at a temperature below -50 ºC (degrees centigrade below zero), keep it at least for 3 minutes, and slow thawing. The cycle is repeated 2 times. Cryosurgery destroys it, but leaves it in place, allowing a very different local result and other changes. Nodes were treated according to the FIGO stage. After anesthesia was able to urinate spontaneously, walk, and have minimal analgesic requirements. After one or two days, they were discharged, with twice-weekly controls. None required flaps or grafts, all maintained vulvar sensitivity and improved their quality of life. Some recovered sexual activity.  “The formation of antibodies after cryosurgery may be caused by damage associated with the technique, which results in the release of massive amounts of ordinarily inaccessible antigens and leads to the production of antibodies. The mechanism involved in studies is in progress: “cryoimmunology” (Prof. Nikolai Korpan). Conclusions: Given technique simplicity, low cost, possibly used in patients with multiple co-morbidities, after any previous treatment, absence of complications, and anatomical and functional results, it can be repeated as many times as necessary, we believe that cryosurgery can be considered among the first options for vulvar cancer treatment.

Medical Doctor: Medicine Faculty, Buenos Aires University 1977. Specialist Gynecology and Obstetrics: Ministry  Health  Argentine 1984. Colposcopist: Argentine Society Lower Genital Tract Pathology and Colposcopy. 2000. Awards: Honor diploma medicine career: Buenos Aires University 1977, Gold Medal: International Society  Cryosurgery (ISC) 2011, Gran Gold Medal: (ISC)  2013. Hospital activity: Hospital Carlos G. Durand. 1979 - 82 Full residence tocogynecology (4 years), 1983 - Head residents, 1984 - Instructor residents, 1984/85 – Assistant doctor in Tocogynecology 1985/91. All of them were rented, by competition.  Honorary Doctor Uterine Cervical Pathology.1991/92 - Member of the cryosurgery working group 1992/2018, Toco-gynecology Assistant Doctor, Head  Lower Genital Tract Pathology and Colposcopy 1999-2014. 2015- to present Honorary Gynecology Consultant. Activity in scientific societies: Argentine Society Lower Genital Tract Pathology and Colposcopy - President 2015-16, Argentine Cryosurgery Society:  - Annual Course Director  2004 – 2013,  - President 2006 -2007 Re-elected 2008-9. International Society  Cryosurgery (ISC): - Vice President  World Congress Cryosurgery. Buenos Aires 2006, Councilor 2011-2016 - Full Member 2017 – to present, - Speaker at World Congresses: Vienna, Argentina, Paris,  United States (USA), Canada, Singapore, Bali, Israel, and Russia. Scientific papers: 47 presented at conferences, 9 publications in magazines, and 2 book chapters, all related to the specialty.