Ahsan Habib
Dhaka Medical College, BangladeshPresentation Title:
Formalin therapy in radiation proctitis
Abstract
Radiotherapy is an essential treatment modality for pelvic malignancies such as gynecological, rectal and prostate cancer. The use of radical doses of radiation in Gynaecological and prostate cancer leads to a significant proportion of patients being cured. However, such high doses also cause the development of significant late toxicities among long-term survivors.Chronic radiation proctopathy (CRP) is one of the most bothersome late toxicities among patients treated with radical pelvic RT. Incidence is reported to be as high as 20%. CRP could occur either as a continuation of acute symptoms 3 months after the completion of RT or symptoms that begin 3 months after the initiation of RT. The median onset is 8–12 months, but onset can occur as late as 30 years. Common symptoms include diarrhea, tenesmus, mucus/blood per rectum, urgency, incontinence, and pain. The complaint of most concern would be rectal bleeding. Refractory hemorrhagic CRP is difficult to manage but previous successful experience in treating cystitis has led to the use of formalin as a treatment option. Topical formalin application has been extensively studied, and most results show that it is a simple, safe and effective way to treat hemorrhagic CRP. Formalin can be applied by direct instillation or by endoscopy-guided placement of formalin-soaked gauze. Formalin acts only on the superficial mucosa, which results in rapid deterioration of mucosal blood flow and superficial coagulation necrosis.
Biography
Ahsan Habib is working as associate professor and head, Department of Colorectal surgery, Dhaka Medical College (1600 bedded and largest hospital in Bangladesh). He completed MBBs from Dhaka medical college in 2000. He completed Fellowship in Surgery 2009, Membership from Royal college in 2008 and Masters in Colorectal surgery 2017. He is a pioneer colorectal surgeon in Government service of Bangladesh. He worked 4 years in National institute of Cancer Research and hospital. There he treated a lot patients suffering from radiation proctitis by 4% Formalin.